Whole Exome Sequencing (DNA)
MI Exome ™ is a high-throughput, next-generation sequencing-based assay that analyzes the whole human exome of approximately 22,000 DNA genes. MI Exome is included with all Caris Molecular Intelligence orders at no additional cost or increase in average turnaround time.
RNA – Superior Method for Fusion Detection,
Caris Molecular Intelligence® tumor profiling includes MI Transcriptome™, Whole Transcriptome Sequencing (WTS), via RNA next-generation sequencing. MI Transcriptome enables gene fusion and splice variant detection from one streamlined test. RNA testing identifies fusions independent of the breakpoints in DNA and, therefore, has the ability to detect rare, novel fusion events better than DNA-based methods.
RNA-Based Fusion Analysis of NTRK1/2/3 Finds 50% More Clinically Actionable NTRK3 Fusion Partners than DNA.
MI Transcriptome™ Whole Transcriptome Sequencing (RNA),
MI Transcriptome™ is a high-throughput RNA sequencing of the whole transcriptome that enables gene fusion detection, RNA splice variant detection and gene expressions analysis all from one streamlined test.